HubLE Methods Committee

Antonia Sophocleous
Cyprus
CO-CHAIR

Mattia
Capulli
Italy
CO-CHAIR

Isabel
Orriss
UK
MEMBER

Jesús
Delgado-Calle
USA
MEMBER

Enrico Dall’Ara
UK
MEMBER

Carmen Huesa
UK
MEMBER

Phil Salmon

ADVISOR

Philippe Clézardin

ADVISOR

Antonia Sophocleous BSc PhD

Antonia is a molecular biologist/biochemist currently based at the European University Cyprus (Nicosia, Cyprus). In addition, she is an Honorary Fellow at the Institute of Genetics and Molecular Medicine, University of Edinburgh (Edinburgh, Scotland, UK).The focus of her research is the role of microbiome on the development of osteoarthritis. She has been an active ECTS delegate since 2007. Besides science, she is regularly involved in public engagement events, and her other hobbies include hiking, cycling, playing the violin and reading.

Mattia Capulli PhD

Mattia is a Medical Biotechnologist currently appointed as Assistant Professor at the University of L’Aquila, Italy. His research focuses on identifying the pathogenic mechanisms and develop novel treatments for rare genetic bone diseases and  breast cancers induced bone metastases. He strongly believes in the necessity of cross-contamination and cross-fertilization for the progress of medical sciences. He was former member of IBMS young investigator committee, member and treasurer of the ECTS Academy. The passion for science continues for Mattia also outside the academia since he is involved in business activities related to genomic. During the free time he loves to enjoy the Italian countryside with his motorbike, and to play saxophone with his blues band.

Isabel Orriss BSc PhD

Isabel is a senior lecturer in Cell and Molecular Biology at the Royal Veterinary College in London (UK).  Her current research encompasses both bone and vascular biology with a particular focus on how local signalling factors regulate bone cell function and vascular calcification. She has played an active role in the UK Bone Research Society (BRS) for many years and is currently the BRS secretary.  As part of this role she is working with other society members to promote the development of early and mid-career scientists working in skeletal research.  Outside of science she enjoys running, skiing and travelling with her family.

Jesus Delgado-Calle PhD

Jesus is a cellular and molecular biologist currently based at the Indiana University School of Medicine (Indianapolis, US). The focus of his research is the role of osteocytes and their-derived factors in bone physiology and pathophysiology. He is an active paper and grant reviewer, he coordinated the Young Investigators group of the Spanish Society of Bone Research and Mineral Metabolism, and is a member of the Engagement and Education Committee of the American Society for Bone and Mineral Research. Besides science, his other passions include soccer and music.

Enrico Dall’Ara PhD

Enrico is a bioengineer based at the Insigneo Institute for in silico medicine and at the Department of Oncology and Metabolism, University of Sheffield (UK). The focus of his research is the development of experimental, imaging and computational modelling methods to characterize preclinically or clinically the effect of musculoskeletal diseases on the bone and joints and to optimise related interventions.  He is currently in the council of the European Society of Biomechanics and he is the President of the UK chapter of the Virtual Physiological Human Institute. In his spare time, Enrico enjoys hiking, soccer, music, and reading.

Carmen Huesa PhD

Carmen Huesa is a bone biologist currently based at the University of Edinburgh (Scotland, UK). The focus of her research is castration resistant prostate cancer bone metastasis. She is an avid supporter of issues and needs of early-career scientists, being one herself. She is a founding member of the ECTS academy, an organisation of early career ECTS members aiming to advance skeletal research through collaboration. Besides science, she spends most of her free time training in Brazilian Jiu Jitsu and is an avid skier.

Phil Salmon PhD

Phil’s PhD research was in bone-seeking radionuclides at Bristol. He then researched bone remodeling and architecture, in academia at the Royal Veterinary College, London with Prof. Lance Lanyon and in industry at AEA Technology, Harwell, using light and confocal histomorphometry for in vivo studies. This experience was the basis of motivation to develop microCT (3D x-ray microscopy) for bone morphometry and other lifescience applications. At Bruker-microCT since 2002 he has been directly involved in the practical implementation of microCT in bone and other life science fields. He has played a role in the development software for 3D quantitative morphometry and micro-densitometry, and invented the widely used “post-scan” method for movement correction in micro-tomography. He has collaborated with surgeons apply microCT to cancer surgery assessment, and has authored numerous peer-reviewed scientific papers.

Philippe Clézardin MSc PhD DSc

Philippe is Research Director at INSERM (Lyon, France) and Professor of Bone Oncology at the University of Sheffield (Sheffield, UK). For the past twenty years, Philippe’s main research interest is in the characterisation of molecular mechanisms that drive bone metastasis formation in breast cancer, with the goal of developing anticancer therapies and novel biomarkers for the identification of patients who are at risk of developing bone metastases. He was President of the Cancer and Bone Society (CABS; 2009-2010). Besides research, he enjoys hiking, skiing and playing golf.