To use in silico modeling, and specifically an agent-based multiphysics model, to assist in the design of clinical trials, and test hypotheses as to bone mechanobiology
To test if inhibition of NF-κB at the level of TRAF6 reduces the aggressive behaviour of breast cancer cell in vitro, ex vivo, and in vivo
To investigate the role of parathyroid hormone-related protein (PTHrP) in cancer anorexia-cachexia syndrome